GUO Linlin, XIE Lu, LIU Yongfang, LI Panpan, GUO Lin. Analysis of infection and related risk factors after heart transplantation in a third-grade class-A hospital from 2018 to 2023[J]. Journal of Clinical Medicine in Practice, 2024, 28(6): 104-107, 112. DOI: 10.7619/jcmp.20233393
Citation: GUO Linlin, XIE Lu, LIU Yongfang, LI Panpan, GUO Lin. Analysis of infection and related risk factors after heart transplantation in a third-grade class-A hospital from 2018 to 2023[J]. Journal of Clinical Medicine in Practice, 2024, 28(6): 104-107, 112. DOI: 10.7619/jcmp.20233393

Analysis of infection and related risk factors after heart transplantation in a third-grade class-A hospital from 2018 to 2023

  • Objective To investigate the infection status after heart transplantation (HT) in a third-grade class-A hospital from 2018 to 2023, and explore its risk factors.
    Methods A retrospective analysis was conducted on the data of 314 patients who underwent HT surgery from January 2018 to July 2023, they were divided into infection group and control group according to postoperative infection situation, the possible influencing factors of HT postoperative infection were analyzed by univariate analysis, and the risk factors of HT postoperative infection were screened by multivariate Logistic regression analysis.
    Results A total of 91 patients(28.98%)developed postoperative infections, with infection sites of respiratory tract and blood. Logistic regression analysis showed that the main risk factors for postoperative infection in HT patients included complicating with chronic lung disease, surgical time ≥5 h, long retention time of postoperative thoracic drainage tube, long postoperative urinary tube retention time, long postoperative mechanical ventilation time, and preoperative Alb < 35 g/L.
    Conclusion Complicating chronic lung disease, surgical time ≥5 h, long postoperative thoracic drainage tube retention time, long postoperative urinary tube retention time, long postoperative mechanical ventilation time, preoperative Alb < 35 g/L are related to postoperative infection of HT. Therefore, active intervention should be carried out for the above factors in patients to reduce the risk of infection.
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