WANG Ying, ZHANG Jianjun. Effect of different vascular access on related indicators in maintenance hemodialysis patients[J]. Journal of Clinical Medicine in Practice, 2019, 23(18): 11-14, 28. DOI: 10.7619/jcmp.201918004
Citation: WANG Ying, ZHANG Jianjun. Effect of different vascular access on related indicators in maintenance hemodialysis patients[J]. Journal of Clinical Medicine in Practice, 2019, 23(18): 11-14, 28. DOI: 10.7619/jcmp.201918004

Effect of different vascular access on related indicators in maintenance hemodialysis patients

  •   Objective  To investigate the effect of different vascular access on related indicators in maintenance hemodialysis patients.
      Methods  Ninety-six patients with maintenance hemodialysis were divided into internal jugular vein with cuff tunnel catheter (CTC) group, central venous catheter (CVC) group, and autologous arteriovenous fistula (AVF) group according to different vascular access. C reactive protein (CRP), hemoglobin (Hb), serum albumin(ALB), interleukin-6 (IL-6), serum phosphorus, blood calcium, erythropoietin (EPO), serum prealbumin (PA), low density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), total cholesterol (TC) levels, left ventricular diastolic dysfunction, left ventricular systolic dysfunction, and incidences of left ventricular hypertrophy as well as complications were compared.
      Results  The levels of CRP and IL-6 in AVF group were significantly lower than those in CVC group and CTC group (P < 0.05). The levels of Hb and ALB in AVF group were significantly higher than those in CVC group and CTC group (P < 0.05). Ventricular diastolic dysfunction, left ventricular systolic dysfunction and the incidence of left ventricular hypertrophy in AVF group were significantly lower than that of CVC group and CTC group (P < 0.05). The levels of serum phosphorus, serum calcium and EPO in AVF group were significantly lower, and PA level was significantly higher than that in CVC group and CTC group (P < 0.05). The levels of LDL, TG and TC in AVF group were significantly lower than those in CVC group and CTC group (P < 0.05). The HDL level in AVF group was significantly higher than that in CVC group and CTC group (P < 0.05); the incidence of complications in the AVF group was significantly lower than that in the CVC group and the CTC group (P < 0.05).
      Conclusion  The vascular access of AVF in maintenance hemodialysis has better efficacy, which has less influence on microinflammation factors.
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