Application value of exhaled nitric oxid detection in treatment of bronchial asthma in adults

  Objective  To explore the application value of exhaled nitric oxide (FeNO) in the treatment of bronchial asthmas in adults.

  Methods  A total of 52 adult patients with bronchial asthma were selected as study group, while 52 healthy subjects were selected as control group during the same period. FeNO and ratio of forced expiratory volume in first second (FEV₁%) were detected in the study group at the time points of before treatment (T₀), 1 month after treatment (T₁), 3 months after treatment (T₂), and 6 months after treatment (T₃). At the same time, the indexes were also detected in the control group. The correlation between FEV₁% and FeNO at different time points was analyzed in the study group.

  Results  FeNO levels at T₁, T₂ and T₃ in the study group were significantly lower than that at T₀, and FeNO levels at T₁ and T₂ in the study group were significantly higher than those in the control group (P < 0.05). The values of FEV₁% at T₁, T₂ and T₃ in the study group were significantly higher than that at T₀, and the values of FEV₁% at T₁ and T₂ in the study group were significantly lower than those in the control group (P < 0.05). FEV₁% value at T₀ was negatively correlated with FeNO level in the study group (P < 0.05).

  Conclusion  FeNO detection plays an important guiding role in the treatment of bronchial asthma in adults.