Abstract: Since December 2019, the rapid spread of coronavirus disease 2019 (COVID-19) poses a serious threat to global public health security. Obstructive sleep apnea hypopnea syndrome (OSAHS) is commonly occurred in patients with COVID-19, however, due to the lack of understanding of their comorbidities, the damage of OSAHS is often underestimated or even ignored. OSAHS has not been identified as an independent risk factor that increases the possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and aggravates the disease. In addition, the understanding of traditional Chinese medicine for the prevention and treatment of novel coronavirus pneumonia complicated with OSAHS at home and abroad is not profound, and related studies are also few. The purpose of this article is to improve clinicians' knowledge and understanding of COVID-19 combined with OSAHS, which may provide some guidance in dealing with this disease.