Objective To investigate the correlations of H-type hypertension with the occurrence, development and poor prognosis of cardiovascular diseases.

Methods From January 2020 to December 2021, a total of 769 hypertensive patients who visited Wanping Community Health Service Center and were contracted with family doctors were selected. According to plasma homocysteine (Hcy) level, the patients were divided into H-type hypertension group (n=362, Hcy≥10 μmol/L) and non-H-type hypertension group (n=407, Hcy < 10 μmol/L). The basic information of patients was collected by questionnaire. The detection rate of H-type hypertension was calculated; the prevalence situation and risk factors of H-type hypertension were analyzed.

Results A total of 769 patients were enrolled, including 362 H-type hypertension patients, with a detection rate of 47.1%. The detection rate of male was 55.5%(151/272), which was significantly higher than 42.5%(211/497) of female (P < 0.05). Carotid intima-media thickness (IMT), waist circumference, glycosylated hemoglobin (HbAlc), uric acid (UA), urea nitrogen (BUN) and triglyceride (TG) in the H-type hypertension group were significantly higher than those in the non-H-type hypertension group, high density lipoprotein cholesterol (HDL-C) and estimated glomerular filtration rate (eGFR) were significantly lower than those in the non-H-type hypertension group (P < 0.05). Male, smoking, elderly, thickened IMT, decreased eGFR, increased waist circumference, increased BUN, increased UA, and increased HbAlc were risk factors for H-type hypertension (P < 0.05).

Conclusion H-type hypertension has a high detection rate in hypertensive patients contracted by family doctors, and is often accompanied by metabolic disorders and target organ damage. Family doctors should pay more attention to patients with H-type hypertension and strengthen their management.