Abstract: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy, and is one of the symptoms that cannot be effectively resolved, which seriously affects the physical and mental health and adaptation level of patients. This paper reviewed the overview of adaptation, assessment tools and CIPN scale of adaptation, influencing factors and intervention measures of adaptation in patients with chemotherapy-induced peripheral neurotoxicity. The factors influencing the adaptation level of patients with chemotherapy-induced peripheral neurotoxicity are complex, the intervention methods need to be further explored and improved, and the intervention effects need to be further verified, which can provide reference for further clinical application and in-depth research in the future.