Abstract: Objective To explore the efficacy of negative pressure lavation in stool collec-tion of patients with diarrhea and to explore the application effect to prevent of incontinent related dermatitis.Methods Ostomy collection bags were put into the anus of 20 patients with diarrhea, and one disposable silicone gastric tube was inserted into the tail of each bag.The tail of the bag was then folded lengthways to cover the gastric tube,which was fixed with adhesive tapes.After that,the tube was connected to an electric sucker,and lukewarm water was poured into the bag to dilute stool.Thus stool was collected after repeated suctions.Results Among 20 patients,only one patient had skin dermatitis at the end of ostomy bag after stopped receiving negative pressure lavation.And the rest patients had stools collected effectively,and no one suffered from incontinent dermatitis.Conclusion Negative pressure lavation is effective in stool collection of patients with diarrhea and prevention of incontinent related dermatitis.It can accurately record the amount of stool,alleviate the pains of patients,and reduce nursing workload.Thus it is worthy of clinical promotion.