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钱志英, 何流, 何晓松, 冯继峰, 唐金海, 潘良熹, 张成阳. 荧光定量PCR法检测食管癌外周血Survivin m-RNA的临床意义[J]. 实用临床医药杂志, 2006, (7): 56-58. DOI: 10.3969/j.issn.1672-2353.2006.07.019
引用本文: 钱志英, 何流, 何晓松, 冯继峰, 唐金海, 潘良熹, 张成阳. 荧光定量PCR法检测食管癌外周血Survivin m-RNA的临床意义[J]. 实用临床医药杂志, 2006, (7): 56-58. DOI: 10.3969/j.issn.1672-2353.2006.07.019
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QIAN Zhi-ying, HE Liu, FEN Ji-feng, TANG Jin-hai, PAN Liang-xi, HE Xia-song, ZHANG Cheng-yang. DETECTION OF APOPTOTIC INHIBITOR GENE SURVIVIN IN PERIPHERAL BLOOD OF ESOPHAGEAL CANCER BY REAL-TIME FLUORESCENCE QUANTITATIVE PCR AND CLINICAL SIGNIFICANCE[J]. Journal of Clinical Medicine in Practice, 2006, (7): 56-58. DOI: 10.3969/j.issn.1672-2353.2006.07.019
Citation: QIAN Zhi-ying, HE Liu, FEN Ji-feng, TANG Jin-hai, PAN Liang-xi, HE Xia-song, ZHANG Cheng-yang. DETECTION OF APOPTOTIC INHIBITOR GENE SURVIVIN IN PERIPHERAL BLOOD OF ESOPHAGEAL CANCER BY REAL-TIME FLUORESCENCE QUANTITATIVE PCR AND CLINICAL SIGNIFICANCE[J]. Journal of Clinical Medicine in Practice, 2006, (7): 56-58. DOI: 10.3969/j.issn.1672-2353.2006.07.019
shu

荧光定量PCR法检测食管癌外周血Survivin m-RNA的临床意义

DETECTION OF APOPTOTIC INHIBITOR GENE SURVIVIN IN PERIPHERAL BLOOD OF ESOPHAGEAL CANCER BY REAL-TIME FLUORESCENCE QUANTITATIVE PCR AND CLINICAL SIGNIFICANCE

    摘要
  • 摘要: 目的 探讨凋亡抑制基因Survivin在食管癌患者外周血中表达的临床意义.方法 共93例食管良、恶性病变患者,采用荧光定量PCR法,检测外周血Survivin m-RNA, 分别观察其在食管良性病变、原位癌及浸润癌患者外周血中的表达强度.结果 Survivin m-RNA在食管良性病变、原位癌及浸润癌患者外周血中均呈渐进性高表达,并与病期有关.结论 外周血中Survivin m-RNA表达强度与食管癌的发生、发展密切相关,实时荧光定量PCR法检测食管癌外周血中Survivin m-RNA, 可方便食管癌的诊断及指导治疗.

     

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