EXPRESSION OF.P53 PROTEIN AND PCNA IN ASTROCYTIC NEOPLASM

Using LSAB immunohistochemical metheds, we examined the P53 and PCNA protein expression in 56 cases of astrocytic neoplasms. The results showed that there is a higher poitive rate in Ⅱ、 Ⅲ ~ Ⅳ class than Ⅰ class in astrocytic neoplasm. There is no obvious difference between Ⅱ and Ⅲ ~ Ⅳ calss. The results suggest that the expression of P53 and PCNA protein play an important role in estimaing the degree of malignance in astrocytic neoplasm.