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WANG Chaoyong, CHEN Deyan, WU Shuangshi, RUAN Binjia, ZHAN Wanda, WEI Fanhao, WANG Yongxiang. Research progress on neuroprotective effect and mechanism of spermidine[J]. Journal of Clinical Medicine in Practice, 2024, 28(2): 124-128. DOI: 10.7619/jcmp.20230862
Citation: WANG Chaoyong, CHEN Deyan, WU Shuangshi, RUAN Binjia, ZHAN Wanda, WEI Fanhao, WANG Yongxiang. Research progress on neuroprotective effect and mechanism of spermidine[J]. Journal of Clinical Medicine in Practice, 2024, 28(2): 124-128. DOI: 10.7619/jcmp.20230862
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Research progress on neuroprotective effect and mechanism of spermidine

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  • Spermidine, as a natural polyamine with high content in nerve cells, plays roles in regulating synaptic plasticity, promoting autophagy, and alleviating oxidative stress in the nervous system. Spermidine and polyamine metabolism may bring new therapeutic ideas for nervous system injury diseases. This paper reviewed the neuroprotective effects and mechanisms of spermidine in nervous system injury diseases.
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