Citation: | LI Xinqiao, SHAN Qianqian, XU Yuanyu, ZHANG Shuai, WANG Zhigang, CHEN Ru, FAN Houbao. Effect of nerve root pulsed radiofrequency on residual neuralgia after operation for lumbar disc herniation[J]. Journal of Clinical Medicine in Practice, 2023, 27(6): 91-95. DOI: 10.7619/jcmp.20223147 |
To explore the effect of nerve root pulse radiofrequency on postoperative residual neuralgia and levels of serum interleukin-1 (IL-1), interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α) in patients with lumbar disc herniation (LDH).
A total of 80 LDH patients with postoperative residual neuralgia were selected and randomly divided into traditional group and study group, with 40 cases in each group. The traditional group was given traditional therapy, while the study group was treated with nerve root pulse radiofrequency. The levels of serum IL-1, IL-8 and TNF-α, the condition of pain[evaluated by the Visual Analogue Scale (VAS)], lumbar function[evaluated by the Japanese Orthopedic Association (JOA) Scores] and clinical efficacy were compared between the two groups.
At the time points of before treatment and 1 month, 3 and 6 months after treatment, the levels of serum IL-1, IL-8 and TNF-α in both groups decreased gradually, and the levels of serum IL-1 and TNF-α at 6 months after treatment in the study group were significantly lower than those in the traditional group (P < 0.05); compared with the VAS score before treatment, the VAS scores at 1 month, 3 and 6 months after treatment in both groups decreased, and the VAS score at 6 months after treatment in the study group was significantly lower than that in the traditional group (P < 0.05). Before treatment, the JOA scores in the study group and the traditional group were (13.15±1.58) and (13.73±1.75) respectively; at 3 and 6 months after treatment, the JOA scores were (17.13±2.14) and (20.12±2.67) respectively in the study group and (15.28±1.89) and (18.78±2.15) respectively in the traditional group, and the JOA scores in the study group were significantly higher than those in the traditional group (P < 0.05). The total effective rate of the study group was 92.50%, which was significantly higher than 70.00% of the traditional group (P < 0.05).
For the LDH patients with postoperative residual neuralgia, nerve root pulse radiofrequency can effectively reduce degree of pain, improve lumbar function, reduce levels of serum IL-1, IL-8 and TNF-α, and alleviate inflammatory reaction.
[1] |
GUPTA A, UPADHYAYA S, YEUNG C M, et al. Does size matter an analysis of the effect of lumbar disc herniation size on the success of nonoperative treatment[J]. Global Spine J, 2020, 10(7): 881-887. doi: 10.1177/2192568219880822
|
[2] |
许海委, 徐宝山, 胡永成, 等. 胸腔镜辅助下侧前路减压融合术治疗腰椎间盘突出症伴椎体后缘骨软骨病[J]. 中华骨科杂志, 2021, 41(7): 405-411.
|
[3] |
武刚, 刘利, 刘振武, 等. 臀上及臀中皮神经松解联合封闭治疗腰椎间盘突出症术后残余神经痛的疗效分析[J]. 颈腰痛杂志, 2019, 40(2): 251-253. https://www.cnki.com.cn/Article/CJFDTOTAL-JYTZ201902036.htm
|
[4] |
毕春娟, 冯利琴, 王晓妮, 等. 补气活血汤联合康复锻炼治疗腰椎间盘突出症患者术后综合征的效果[J]. 实用临床医药杂志, 2020, 24(3): 115-117. doi: 10.7619/jcmp.202003033
|
[5] |
王岩, 李吉平. 针灸配合骶管封闭治疗对腰椎间盘突出症术后腰腿痛的效果[J]. 中国卫生标准管理, 2022, 13(7): 125-128. https://www.cnki.com.cn/Article/CJFDTOTAL-WSBZ202207033.htm
|
[6] |
谭响, 谢继勇, 谢金岑, 等. PELD联合硬膜外注射糖皮质激素治疗腰椎间盘突出症的临床疗效观察[J]. 重庆医学, 2020, 49(6): 918-921. https://www.cnki.com.cn/Article/CJFDTOTAL-CQYX202006013.htm
|
[7] |
肖源勋, 黄国威, 郭佳妮, 等. MRI导航腰脊神经后根节脉冲射频的疗效观察[J]. 中国疼痛医学杂志, 2020, 26(1): 76-80. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202001021.htm
|
[8] |
CHEN K T, TSENG C, SUN L W, et al. Technical considerations of interlaminar approach for lumbar disc herniation[J]. World Neurosurg, 2021, 145: 612-620.
|
[9] |
张志芳. 认知行为干预配合腰腹肌肌力训练对腰椎间盘突出症患者术后康复的影响分析[J]. 实用医药杂志, 2019, 36(8): 749-751, 755. https://www.cnki.com.cn/Article/CJFDTOTAL-QEYY201908028.htm
|
[10] |
李俊杰, 梁舒涵, 吴从俊, 等. 壮腰祛瘀方治疗腰椎间盘突出症术后残留症状的临床研究[J]. 中国中医骨伤科杂志, 2020, 28(2): 24-28. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZG202002027.htm
|
[11] |
武刚, 刘利, 刘振武, 等. 臀上及臀中皮神经松解联合封闭治疗腰椎间盘突出症术后残余神经痛的疗效分析[J]. 颈腰痛杂志, 2019, 40(2): 251-253. https://www.cnki.com.cn/Article/CJFDTOTAL-JYTZ201902036.htm
|
[12] |
GERDES S, VELASCO M, WU J J, et al. Calcipotriol/betamethasone dipropionate aerosol foam for the treatment of psoriasis vulgaris: a review of real-world evidence (RWE)[J]. J Dermatolog Treat, 2021, 32(8): 883-893.
|
[13] |
孟泽祖, 叶正旭, 万博. 关节腔内注射复方倍他米松注射液联合体外冲击波治疗疼痛性肩关节挛缩症临床疗效观察[J]. 陕西医学杂志, 2021, 50(6): 682-686. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYZ202106010.htm
|
[14] |
方斌, 黄洪斌, 曾婷婷. 脉冲射频治疗对腰椎间盘突出症患者血清炎症因子水平的影响[J]. 临床检验杂志: 电子版, 2019, 8(4): 249-250. https://www.cnki.com.cn/Article/CJFDTOTAL-LNJI201904211.htm
|
[15] |
SHIN D, JI S, LEE D, et al. Deep reinforcement learning designed shinnar-le roux RF pulse using root-flipping: DeepRFSLR[J]. IEEE Trans Med Imaging, 2020, 39(12): 4391-4400.
|
[16] |
吴大胜, 刘炎, 刘娜, 等. 脉冲射频降低NF-κB磷酸化水平治疗腰椎间盘突出症病人的疼痛[J]. 中国疼痛医学杂志, 2020, 26(11): 871-873. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202011018.htm
|
[17] |
李洪涛, 魏心然, 孙晓伟, 等. 脊痛消胶囊对腰椎间盘突出症的疗效及对IL-1β、IL-6、TNF-α因子的影响[J]. 中医药信息, 2020, 37(2): 95-99. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN202002023.htm
|
[18] |
ZHANG Q S, DU P J, ZHANG Y N. The effect of locating and sliding of facet combined with percutaneous endoscopic lumbar discectomy on cell inflammatory indicators and the treatment of disc herniation[J]. Cell Mol Biol (Noisy-le-grand), 2022, 67(5): 181-187.
|
[19] |
GUO Y F, LI C, SHEN B D, et al. Is there any relationship between plasma IL-6 and TNF-α levels and lumbar disc degeneration?A retrospective single-center study[J]. Dis Markers, 2022, 2022: 6842130.
|
[20] |
魏胜全, 薛华, 王惠霞, 等. 孟鲁司特联合噻托溴铵对支气管哮喘缓解期患者的影响[J]. 实用临床医药杂志, 2020, 24(14): 48-52. doi: 10.7619/jcmp.202014013
|
[21] |
方勇, 王朝晖, 李凌霄, 等. 射频热凝联合脉冲射频治疗腰椎间盘突出症的疗效及对患者血清白细胞介素8、趋化因子10的影响[J]. 中国基层医药, 2020, 27(17): 2102-2106.
|