GAO Xue, WANG Yonghuai, WANG Yao, LIANG Jie, WEI Fengying, LOU Zhe. Diagnostic value of Gray-Weale classification in symptomatic carotid plaque[J]. Journal of Clinical Medicine in Practice, 2022, 26(13): 41-44. DOI: 10.7619/jcmp.20220075
Citation: GAO Xue, WANG Yonghuai, WANG Yao, LIANG Jie, WEI Fengying, LOU Zhe. Diagnostic value of Gray-Weale classification in symptomatic carotid plaque[J]. Journal of Clinical Medicine in Practice, 2022, 26(13): 41-44. DOI: 10.7619/jcmp.20220075

Diagnostic value of Gray-Weale classification in symptomatic carotid plaque

More Information
  • Received Date: January 05, 2022
  • Available Online: July 01, 2022
  • Objective 

    To investigate the distribution characteristics and clinical application value of Gray-Weale (GW) classification of symptomatic carotid plaque.

    Methods 

    Sixty inpatients with carotid artery bifurcation atherosclerosis (AS) plaques undergoing carotid doppler ultrasonography were randomly selected. Patients were divided into symptomatic group (n=32) and asymptomatic group (n=28) according to whether they had experienced an ischemic cerebrovascular event within 6 months. The GW classification of patients'plaques was analyzed. Carotid artery bifurcation plaque thickness, plaque length and the number of plaque were evaluated by ultrasound.

    Results 

    A total of 60 carotid bifurcation plaques were analyzed by GW classification, 32 plaques in symptom group, including 6 with typeⅠ, 17 with type Ⅱ, 7 with type Ⅲ, and 2 with type Ⅴ; there were 28 plaques in asymptomatic group, including 2 plaques in type Ⅰ, 7 plaques in type Ⅱ, 17 plaques in type Ⅲ, 2 plaques in type Ⅳ. There was statistically significant difference between the two groups in GW classification (P < 0.05). The plaque thickness in the symptomatic group was significantly higher than that in the asymptomatic group (P < 0.05). There was a negative correlation between plaque GW classification and plaque thickness (r=-0.53, P < 0.01). Cohen's Kappa consistency test results showed that Cohen's Kappa coefficient was 0.874 (95%CI, 0.766 2 to 0.981 8, P < 0.001).

    Conclusion 

    GW plaque classification has good stability and repeatability in evaluating echo characteristics of carotid atherosclerotic plaques. Plaque GW classification can be used as an effective method to screen symptomatic carotid plaque.

  • [1]
    《中国脑卒中防治报告》编写组. 《中国脑卒中防治报告2019》概要[J]. 中国脑血管病杂志, 2020, 17(5): 272-281.
    [2]
    LYU Q, TIAN X J, DING Y F, et al. Evaluation of carotid plaque rupture and neovascularization by contrast-enhanced ultrasound imaging: an exploratory study based on histopathology[J]. Transl Stroke Res, 2021, 12(1): 49-56. doi: 10.1007/s12975-020-00825-w
    [3]
    HUIBERS A, DE BORST G J, WAN S, et al. Non-invasive carotid artery imaging to identify the vulnerable plaque: current status and future goals[J]. Eur J Vasc Endovasc Surg, 2015, 50(5): 563-572. doi: 10.1016/j.ejvs.2015.06.113
    [4]
    华扬, 惠品晶, 邢瑛琦. 中国脑卒中血管超声检查指导规范[J]. 中华医学超声杂志: 电子版, 2015, 12(8): 599-610. doi: 10.3877/cma.j.issn.1672-6448.2015.08.004
    [5]
    GRAY-WEALE A C, GRAHAM J C, BURNETT J R, et al. Carotid artery atheroma: comparison of preoperative B-mode ultrasound appearance with carotid endarterectomy specimen pathology[J]. J Cardiovasc Surg (Torino), 1988, 29(6): 676-681.
    [6]
    GEROULAKOS G, RAMASWAMI G, NICOLAIDES A, et al. Characterization of symptomatic and asymptomatic carotid plaques using high-resolution real-time ultrasonography[J]. Br J Surg, 1993, 80(10): 1274-1277.
    [7]
    LOU Z, YANG J, TANG L, et al. Shear wave elastography imaging for the features of symptomatic carotid plaques: a feasibility study[J]. J Ultrasound Med, 2017, 36(6): 1213-1223. doi: 10.7863/ultra.16.04073
    [8]
    ADDIS D R, TOWNSLEY M M. Implications of carotid arterial plaque assessment by ultrasound for the cardiothoracic anesthesiologist: an overview of the 2020 American society of echocardiography recommendations for the assessment of carotid arterial plaque by ultrasound for the characterization of atherosclerosis and evaluation of cardiovascular risk[J]. J Cardiothorac Vasc Anesth, 2021, 35(4): 987-990. doi: 10.1053/j.jvca.2020.12.006
    [9]
    SPENCE J D. Measurement of carotid plaque burden[J]. Curr Opin Lipidol, 2020, 31(5): 291-298. doi: 10.1097/MOL.0000000000000706
    [10]
    VERGALLO R, PORTO I, D'AMARIO D, et al. Coronary atherosclerotic phenotype and plaque healing in patients with recurrent acute coronary syndromes compared with patients with long-term clinical stability: an in vivo optical coherence tomography study[J]. JAMA Cardiol, 2019, 4(4): 321-329. doi: 10.1001/jamacardio.2019.0275
    [11]
    SHIMOKADO A, MATSUO Y, KUBO T, et al. In vivo optical coherence tomography imaging and histopathology of healed coronary plaques[J]. Atherosclerosis, 2018, 275: 35-42. doi: 10.1016/j.atherosclerosis.2018.05.025
    [12]
    SANGIORGI G, ROVERSI S, BIONDI ZOCCAI G, et al. Sex-related differences in carotid plaque features and inflammation[J]. J Vasc Surg, 2013, 57(2): 338-344. doi: 10.1016/j.jvs.2012.07.052
    [13]
    BRINJIKJI W, RABINSTEIN A A, LANZINO G, et al. Ultrasound characteristics of symptomatic carotid plaques: a systematic review and meta-analysis[J]. Cerebrovasc Dis, 2015, 40(3/4): 165-174.
    [14]
    BEG F, REHMAN H, AL-MALLAH M H. The vulnerable plaque: recent advances in computed tomography imaging to identify the vulnerable patient[J]. Curr Atheroscler Rep, 2020, 22(10): 58. doi: 10.1007/s11883-020-00879-z
    [15]
    HOWARD D P, VAN LAMMEREN G W, ROTHWELL P M, et al. Symptomatic carotid atherosclerotic disease: correlations between plaque composition and ipsilateral stroke risk[J]. Stroke, 2015, 46(1): 182-189. doi: 10.1161/STROKEAHA.114.007221

Catalog

    Article views (222) PDF downloads (18) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return