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LU Huamei, CAI Jing, YUAN Zhiping. Changes of Q-Tc interval in patients with posthepatitis B cirrhosis and its clinical significance[J]. Journal of Clinical Medicine in Practice, 2021, 25(19): 57-61. DOI: 10.7619/jcmp.20211446
Citation: LU Huamei, CAI Jing, YUAN Zhiping. Changes of Q-Tc interval in patients with posthepatitis B cirrhosis and its clinical significance[J]. Journal of Clinical Medicine in Practice, 2021, 25(19): 57-61. DOI: 10.7619/jcmp.20211446
shu

Changes of Q-Tc interval in patients with posthepatitis B cirrhosis and its clinical significance

  • 1.

    Department of Gastroenterology, Wujin Hospital Affiliated to Jiangsu University, Changzhou, Jiangsu, 213002

  • 2.

    Department of Gastroenterology, Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, 213002

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  • Received Date: April 01, 2021
  • Available Online: October 27, 2021
  • Published Date: October 14, 2021
    Graphical Abstract
    • Abstract
  •   Objective  To analyze the changes of Q-Tc in electrocardiogram and its related factors in patients with posthepatitis B cirrhosis.
      Methods  The clinical data of 80 patients with viral hepatitis B cirrhosis (cirrhosis group) was retrospectively analyzed. The general data of the cirrhosis group and 30 chronic hepatitis B patients (control group) was compared. The changes of electrocardiogram in Q-Tc interval were analyzed. The relationships between Child-Pugh score, grade and degree of cirrhosis was analyzed.
      Results  The levels of serum sodium, serum calcium, serum albumin, hemoglobin and platelet in the cirrhosis group were significantly lower, while the levels of serum bilirubin and aspartate aminotransferase were significantly higher, and prothrombin time was significantly longer than that in the control group (P < 0.05). The heart rate in the cirrhosis group was significantly higner, and the Q-Tc interval was significantly longer than that in the control group (P < 0.05). The Q-Tc interval was positively correlated with Child-Pugh score (r=0.38, P < 0.01), but negatively correlated with serum albumin (r=-0.31, P=0.006) and hemoglobin (r=-0.29, P=0.010); Child-pugh score was an independent correlation factor affecting the electrocardiogram Q-Tc interval in patients with cirrhosis.
      Conclusion  Q-Tc is prolonged in patients with cirrhosis and it is correlated with Child-Pugh score. The detection of Q-Tc interval changes has clinical guiding significance for knowing the severity of cirrhosis.
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    • References (15)
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