Objective To analyze the influencing factors of long-term prognosis in patients with maintenance peritoneal dialysis (PD).
Methods The clinical materials of 209 PD patients treated in Nanjing Drum Tower Hospital from January 2006 to August 2015 were analyzed retrospectively, the survival rate and technical survival rate were calculated, and the risk factors influencing prognosis were analyzed. Kidney transplantation was performed in 11 PD patients within 5 years of treatment. According to the dialysis age of the rest patients, 110 patients were enrolled in long-term PD group (dialysis age ≥ 5 years) and 88 patients in short-term PD group (dialysis age < 5 years), and the influencing factors of dialysis age were analyzed.
Results The 1-, 3-, 5-, 8- and 10-year cumulative survival rates of 209 PD patients were 97.5%, 87.7%, 72.0%, 54.9% and 7.0% respectively, and the cumulative technical survival rates were 94.7%, 83.8%, 73.2%, 52.7% and 44.3% respectively. COX multivariate regression analysis showed that the older age during catheterization, less urine volume before PD, self-paid medical treatment, non-primary glomerulonephritis and cardiovascular diseases were the independent risk factors of death in PD patients (P < 0.05). Older age during catheterization, self-paid medical treatment and peritonitis were the independent risk factors of technical failure (P < 0.05). Logistic regression analysis showed that age during catheterization, urine volume before PD and compliance of follow-up were the independent risk factors of dialysis age (P < 0.05).
Conclusion Age, compliance of follow-up and urine volume before PD are independent risk factors of dialysis age. It is helpful to improve the quality of life and prolong dialysis time by actively preventing and controlling infection, strengthening follow-up management and protecting the residual renal function.
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