objective To analyze influencing factors of hypercholesterolemia in the elderly based on propensity score.
Methods A total of 763 elderly people aged over 65 years who underwent physical examinations were selected as research objects. All the objects underwent physical examinations and their fasting blood samples were collected. According to the cholesterol levels, they were divided into hypercholesterolemia and non-hypercholesterolemia group, propensity score matching module of SPSS 23.0 software analysis was used to analyze the related factors of hypercholesterolemia.
Results The levels of triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (Apo A1) and apolipoprotein B (Apo B) in the hypercholesterolemia group were significantly higher than those in non-hypercholesterolemia group(P < 0.01). Logistic multiple regression analysis suggested that the increase of TG, HDL-C, Apo A1 and the decrease of TBIL, DBIL were independently associated with hypercholesterolemia(P < 0.01). The results of propensity score matching showed that elevated levels of TG, HDL-C, LDL-C, Apo A1 as well as Apo B, and decreased levels of TBIL and DBIL were risk factors for hypercholesterolemia(P < 0.05 or P < 0.01).
Conclusion The prevalence of hypercholesterolemia in the elderly is higher, and elevated levels of TG, HDL-C, LDL-C, Apo A1 as well as Apo B, and decreased levels of TBIL and DBIL are risk factors for hypercholesterolemia.
DownLoad: