Objective To explore the relationship between monocyte to high-density lipoprotein cholesterol ratio(MHR)and carotid artery stenosis(CAS) in patients with acute cerebral infarction(ACI).
Methods A total of 242 ACI patients were selected as study objects, among whom 41 cases without CAS were selected as control group and 201 patients with CAS were selected as stenosis group. According to the ultrasonic results, the stenosis group was further divided into mild stenosis group (n=88), moderate stenosis group (n=61), severe stenosis and occlusion group (n=52). Logistic regression analysis was used to determine the risk factors of CAS in ACI patients, and ROC curve was used to assess the predictive value of MHR in ACI patients with CAS.
Results The MHR of the stenosis group was significantly higher than that of the control group (P < 0.05). The MHR values of the moderate stenosis group, severe stenosis and occlusion group were significantly higher than those of the control group (P < 0.05). Logistic regression analysis showed that MHR was an independent risk factor for CAS in ACI patients. Receiver operating characteristic (ROC) curve results suggested that when the MHR value was 0.535, the maximum predictive value of CAS for ACI patients was the highest, sensitivity was 40.30%, and specificity was 85.40%(P < 0.05).
Conclusion MHR is an independent risk factor, and may be an indicator to predict CAS in ACI patients.
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