Objective To investigate the effect of albumin combined with plasma transfusion on duration of shock and renal function in patients with hemorrhagic fever shock with renal syndrome.
Methods A total of 100 patients with hemorrhagic fever shock with renal syndrome in the hospital were divided into two groups by random number table method, with 50 cases in each group. Control group was given routine treatment, and observation group was treated with albumin combined with plasma transfusion. The duration of shock, renal function, inflammatory factors, incidences of complications were compared between two groups.
Results The duration of shock in observation group was shorter than that in control group, and the difference was statistically significant (P < 0.01); after treatment, the levels of blood urea nitrogen (BUN) and serum creatinine (Scr) in observation group were lower than those in control group (P < 0.05); after treatment, the levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in observation group were lower than those in control group (P < 0.05); the incidences of exudative pneumonia, secondary bacteremia, multiple organ hemorrhage in observation group were lower than that in control group (P < 0.05).
Conclusion Albumin combined with plasma transfusion for patients with hemorrhagic fever shock with renal syndrome can shorten duration of shock, improve renal function, relieve inflammatory response, and reduce complications.
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