Objective To study the clinical significance of blood lipid level in patients with gestational diabetes mellitus (GDM) in late pregnancy and its impact on neonates.
Methods A total of 101 GDM patients were selected as GDM group, and 103 pregnant women with normal glucose tolerance in the same period were as control group. The neonatal weight, incidence of fetal macrosomia and weight gaining of puerperas in both groups were evaluated.
Results Patients in GDM group was older than those in control group, and the total cholesterol (TC) level in GDM group was higher than that in control group (P < 0.05). A higher neonatal weight and incidence of macrosomia was found in GDM group compared with control group (P < 0.05). However, there were no significant differences in weight of fetal macrosomia, and Apgar scores at birth and 5 min after birth in two groups (P>0.05).
Conclusion GDM is mostly accompanied with abnormal lipid metabolism during abnormal glucose metabolism process. Therefore, attention should be paid not only to diet control, proper exercise, and rational use of insulin, but also to monitoring of blood lipid, insulin resistance reduction, and improvement of pregnancy outcomes, thus ensuring the maternal and child health.
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