Objective To explore the efficacy of enema with traditional Chinese medicine combined with needle-warming moxibustion in the treatment of chronic distal ulcerative colitis.
Methods A total of 90 patients with distal ulcerative colitis were divided into three groups. On the basis of routine western medicine, Chinese medicine enema group was treated with Chinese medicine for enema, needle-warming moxibustion group was treated with needle-warming moxibustion, and combined treatment group was treated with Chinese medicine for enema and needle-warming moxibustion. The clinical efficacy, biochemical indicators and inflammatory factors, TCM symptom score, colonoscopy score, colon histopathological score, mucosal healing and recurrence, and adverse reactions of the two groups were compared.
Results The total effective rate of combined treatment group was significantly higher than that of Chinese medicine enema group and needle-warming moxibustion group (P < 0.05). The levels of white blood cell count (WBC), platelet (PLT), tumor necrosis factor-α (TNF-α) and interleukin-8 (IL-8) after treatment in combined treatment group were significantly lower than those in Chinese medicine enema group and needle-warming moxibustion group (P < 0.05). After treatment, TCM symptom score, colonoscopy score and colon histopathological score in combined treatment group were significantly lower than those of Chinese medicine enema group and needle-warming moxibustion group (P < 0.05), and mucosal healing rate and recurrence rate were significantly better than those of Chinese medicine enema group and needle-warming moxibustion group (P < 0.05). There were no significant differences in the incidence rate of adverse reactions among the three groups (P>0.05).
Conclusion Traditional Chinese medicine for enema combined with needle-warming moxibustion is effective in the treatment of chronic distal ulcerative colitis, which can significantly improve the TCM symptoms and reduce the levels of biochemical indicators and inflammatory factors.
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