Therapeutic selection of endoscopic varices of gastric fundus and analysis for re-bleeding

  Objective  To investigate the selection of endoscopic treatment for varices of gastric fundus and analysis for rebleeding.

  Methods  A total of 68 patients with gastric varices were divided into two groups. Group A was treated with tissue adhesive injection combined with sclerotherapy. Group B were treated with endoscopic ligation combined with tissue adhesive injection. The clinical efficacy, hemostatic condition, conditions of varicose eradication, hospital stay, rehaemorrhagia, 1-year survival rate and complications were observed and compared between the two groups.

  Results  The total effective rate, hemostasis rate at 1 d after treatment and varicose eradication rate of group B were slightly higher than those of group A, but the differences showed no statistically significant (P>0.05); The hemostasis rate at 7 d after treatment in group B was significantly higher, and the length of hospital stay was significantly shorter than that in group A(P < 0.05). The recent rehaemorrhagia rate of group B was slightly lower than that of group A, but the difference was not statistically significant(P>0.05). The long-term rehaemorrhagia rate of group B was significantly lower(P < 0.05). The 1-year survival rate of group B was slightly higher than that of group A, but the difference was not statistically significant(P>0.05); The incidence of complications in group B was significantly lower than that in group A (P < 0.05).

  Conclusion  Endoscopic ligation combined with tissue adhesive injection for patients with gastric variceal bleeding has good therapeutic effects, and better outcomes in hemostasis rate, long-term rehaemorrhagia rate and complication rate than tissue adhesive injection combined with sclerotherapy.