Objective To explore the high-risk factors of 28-day mortality in sepsis patients.
Methods The clinical materials of 168 patients with sepsis were retrospectively analyzed. Defining the death within 28 days after diagnosis as the end point, the related factors of death was analyzed.
Results Age, Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ) score, shock, C reactive protein (CRP), lactic acid (Lac) were the independent risk factors of 28-day mortality in sepsis patients (OR>1, P < 0.05), while VitD was an independent protective factor (OR < 1, P < 0.05). The values of area under curve (AUC) of receiver operating characteristic curve (ROC) of the factors mentioned above were significantly larger than the reference line (P < 0.05).
Conclusion The 28-day mortality of sepsis patients is independently affected by age, APACHE Ⅱscore, shock, CRP, Lac, and VitD.
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