Effect of pressure control ventilation versus volumecontrol ventilation for surgical patients in prone position: a Meta-analysis

  Objective  To compare the efficacy of pressure control ventilation(PCV) versus volume control ventilation(VCV) for surgical patients in prone position.

  Methods  The random control trials(RCT) were searched in the database of PubMed, EMbase, The Cochrane Library, WanFang for the efficacy of PCV versus VCV for surgical patients in prone position. Two researchers collected and screened the data separately, the quality of studies was evaluated by using the Cochrane Collaboration′s net work, and Meta analysis was performed by RevMan 5.3 software.

  Results  Seven RCTs with a total of 267 patients, of whom 134 received PCV and 133 received VCV, in accordance with the criteria were included in the study. Compared with VCV group, PCV group had reduced intraoperative peak airway pressure(WMD=-2.08 cmH₂O, 95%CI: -2.78~-1.34 cmH²O), plateau airway pressure(WMD=-1.49 cmH₂O, 95%CI: -2.81~-0.17 cmH₂O), improved intraoperative dynamic compliance(WMD=5.36 mL/cmH₂O, 95%CI: 3.47~7.25 mL/cmH₂O), as well as higher mean airway pressure(WMD=0.77 cmH₂O, 95% CI: 0.10~1.45 cmH₂O).

  Conclusion  Compared with VCV, PCV can maintain a stable airway pressure and reduce airway-related complications for surgical patients with mechanical ventilation in prone position.