MA Congcong, Liu Yanqin. Changes of blood lipid levels in patients with multiple myeloma and its clinical significance[J]. Journal of Clinical Medicine in Practice, 2014, (7): 113-115. DOI: 10.7619/jcmp.201407038
Citation: MA Congcong, Liu Yanqin. Changes of blood lipid levels in patients with multiple myeloma and its clinical significance[J]. Journal of Clinical Medicine in Practice, 2014, (7): 113-115. DOI: 10.7619/jcmp.201407038

Changes of blood lipid levels in patients with multiple myeloma and its clinical significance

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  • Published Date: July 14, 2014
  • Objective To investigate the changes of blood lipid in the patients with multiple myeloma (MM)and the relationship with clinical stage.Methods 112 initially-diagnosed patients with MM and 80 healthy people were respectively as MM group and normal control group.The lev-els of blood lipid before chemotherapy in two groups and MM patients with different clinical stages as well as the levels before and after chemotherapy were compared.Triglyceride (TG),total choles-terol (TC),high density lipoprotein cholesterol (HDL-C)and low density lipoprotein cholesterol (LDL-C)were included.Results Before chemotherapy,the levels of TC,HDL-C and LDL-C in MM group were significantly lower than that in normal control group,but the difference was not significant compared with TG levels.The levels of TC,HDL-C and LDL-C in phase Ⅲ and LDL-C in phase Ⅱ were all significantly lower than that in normal control group,and the difference was not significant compared with the levels of blood lipid in phase Ⅰ.After 2 courses of chemotherapy,the levels of TC and HDL-C in effectively treated patients were obviously higher than that before chemotherapy.Conclusion The level of blood lipid is helpful to diagnose patients with MM and to evaluate the clinical staging and prognosis.
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