Clinical value of perioperative prophylactic use of antibiotics in gynaecology and obstetrics department
-
摘要: 目的 探讨妇产科围术期预防性应用抗生素的临床价值.方法 将152例妇产科手术患者随机分为2组,每组76例.观察组于术前30 min内静滴头孢呋辛钠l 5 g/次,并于术后6h重复给药1次；对照组仅于术后静滴头孢呋辛钠1.5g,2次/d.比较2组患者术后最高体温、退热时间、住院时间、术后感染情况及不良反应的差异.结果 对照组患者术后最高体温、退热时间、住院时间及术后感染发生率均显著大于观察组；2组不良反应发生率无显著差异.结论 妇产科围术期预防性应用抗生素与仅术后应用抗生素比较,术后最高体温、退热时间、住院时间及术后感染率均得到显著降低或缩短,说明该方法安全可靠,具有较高的临床应用价值,值得推广.
-
-
Setiawan B. The role of prophylactic antibiotics in preventing perioperative infection [J]. Acta Medica Indonesiana, 2011(4):262. 赵状平. 妇产科围术期预防性应用抗生素的现状及循证评价 [J]. 临床合理用药杂志, 2011(5):97. 中华人民共和国卫生部. 卫生部办公厅关于抗菌药物临床应用管理有关问题的通知 [Z]. 2009. Gunn B, Ali S, Abdo-Rabbo A. An investigation into perioperative antibiotic use during lower segment caesarean sections (LSCS) in four hospitals in Oman [J]. Oman Med J, 2009(3):179. Witt A, D?ner M, Petricevic L. Antibiotic prophylaxis before surgery vs after cord clamping in elective cesarean delivery:a double-blind, prospective, randomized, placebo-controlled trial [J]. Archives of Surgery, 2011, (12):1404. Moslemi M K, Movahed S M, Heidari A. Comparative evaluation of prophylactic single-dose intravenous antibiotic with postoperative antibiotics in elective urologic surgery [J]. Ther Clin Risk Manag, 2010.551. 黄甘颖. 剖宫产术围术期预防性应用抗生素的临床观察 [J]. 现代中西医结合杂志, 2008, (26):4121. Costantine M M, Rahman M, Ghulmiyah L. Timing of pcrioperative antibiotics for cesarean delivery:a meta analysis [J]. American Journal of Obstetrics and Gynecology, 2008(3):301.
计量
- 文章访问数: 160
- HTML全文浏览量: 53
- PDF下载量: 2
下载:
苏公网安备 32100302010246号