Abstract: Aim: to compare the efficacy of Felodipine - ER with that of Bezanapril. Method: ahundred and thirty patients with essential hypertension were randomly divided into Felodipine - ER group(F group) and Bezanpril group (B group). 123 patients completed the study. Result: alI the reductionof BP in F group was more than that in B group. But the difference between two groups wasn' t statisti-cally significant (P 0. 05). After 2 weeks, the total effective rate in F group was 66. 7%, whereasit in B group was 48. 7% (P 0.05). After 4 weeks, the total effective rate was 87. 3% and 68.3% respectively (P 0.05). The inciclance of adverse effects was lower and adveres effects were mild.Condusion: both Felodipine - ER and Bezanapril are effective and well toleraled in freating the essential hy-pertension. However, Felodipine - ER 5 ～ 10mg/d is more effective than Bezanapril 10～ 20mg/d in con-troling high blood pressure.