56株肺炎克雷伯菌临床分离株的菌体蛋白分析和耐药性初步鉴定

IDENTIFICATION OF BACTERIAL PROTEIN ANALYSIS AND DRUG RESISTANCE OF ISOLATED STRAINS FROM 56 KLEBSIELLA PNEUMONIAE

摘要: 从临床腹泻病人粪便桥本中分离出56株肺炎杆菌，对其部分生物学特性作了初步鉴定．用SDS－PAGE分析菌体蛋白，可见基本相同的17条区带。56株肺炎杆菌对头孢唑淋的耐药率为14．3％，对庆大霉素和氯霉素的耐药率分别为50．0％和57．1％，对其余9种抗生素的耐药率均在60％以上。由于抗生素的不合理使用等原因，近年来肺炎克雷伯首的耐药享有上升的趋势。

Abstract: Fifty -six strains of klebsiella pneumoniae were isolated from stools of diarrhoea pa-tients. Bacterial proteins were examined by sodium dodecyl sulfate - polyac rylamide gel electrophoresis. Sev-enteen. distinct profiles were differentiated. Fourteen percent of 56 strains of K. pneumoniae was resistantto cefazolin. Forty percent (28/56) and forty-seven percent (32/56) strains were resistant to gentamicinand chloramphnicol respectively- The resistant rate was on the rise.