细菌纳米纤维素制备小口径人工血管的研究进展

Research progress on bacterial nanocellulose in the preparation of small-diameter artificial blood vessels

摘要: 人工血管作为一种重要的血管替代物,已被广泛应用于血管介入治疗和血管重建手术中。小口径人工血管(直径<6 mm)由于口径小、流速慢、血压低、血流环境复杂等原因，长期植入时仍面临一些挑战。细菌纳米纤维素(BNC)作为一种天然高分子材料，通过复合改性和表面修饰增强小口径人工血管的再生作用和修复效果。本文综述了BNC制备小口径人工血管的研究进展，并讨论了BNC修饰人工血管的优势和潜在应用前景。

Abstract: Artificial blood vessels, serving as crucial vascular substitutes, have been widely utilized in vascular interventional therapies and revascularization surgeries. Small-diameter artificial blood vessels (diameter< 6 mm) pose challenges for long-term implantation due to their small diameter, slow flow velocity, low blood pressure, and complex blood flow environment. Bacterial nanocellulose (BNC), a natural polymer material, enhances the regenerative and repair effects of small-diameter artificial blood vessels through composite modification and surface modification. This article reviewed the research progress in the preparation of small-diameter artificial blood vessels using BNC and discussed the advantages and potential application prospects of BNC artificial blood vessels.