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辨证推拿辅助治疗小儿难治性支原体肺炎的效果观察

Effect of dialectical massage in the auxiliary treatment of refractory Mycoplasma pneumonia in children

    摘要
  • 摘要:
    目的 分析辨证推拿辅助治疗小儿难治性支原体肺炎(RMPP)对炎症指标、肺功能的影响。
    方法 选择河北省第七人民医院2022年9月—2023年8月就诊的320例RMPP患儿为研究对象，根据治疗方法不同将其分为2组，每组160例。西医组给予常规抗炎等对症治疗，推拿组在西医组基础上给予辨证推拿治疗。比较2组临床疗效、临床症状消失时间、肺功能指标、血清炎症因子、免疫功能指标、不良反应总发生率。
    结果 推拿组临床总有效率高于西医组，差异有统计学意义(P < 0.05)。推拿组发热、咳嗽、咳痰、肺部湿啰音消失时间均较西医组更短，差异有统计学意义(P < 0.05)。推拿组治疗后最大呼气流量(PEF)、最大呼气中期流量(MMEF)、用力肺活量(FVC)均较西医组更高，血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平均较西医组更低，差异有统计学意义(P < 0.05)。推拿组治疗后CD3+、CD4+、CD4+/CD8+均较西医组更高, CD8+较西医组更低，差异有统计学意义(P < 0.05)。推拿组不良反应总发生率与西医组比较，差异无统计学意义(P>0.05)。
    结论 辨证推拿联合西药可有效缓解RMPP患儿发热、咳嗽等症状，减轻炎症反应，改善肺功能及免疫功能，且不良反应较少。

     

    Abstract:
    Objective To analyze the effects of massage therapy on the inflammatory state and lung function of pediatric refractory Mycoplasma pneumonia (RMPP).
    Methods A total of 320 children with RMPP treated in Hebei Seventh People′s Hospital from September 2022 to August 2023 were selected in the study. According to different treatment methods, they were divided into two groups, with 160 cases in each group. The western medicine group was given conventional anti-inflammatory and other symptomatic treatment, while the massage group was given dialectical massage treatment based on the western medicine group. The clinical efficacy, duration of disappearance of clinical symptoms, pulmonary function indexes, serum inflammatory factors, immune function indexes and total incidence of adverse reactions were compared between the two groups.
    Results The total effective rate of massage group was higher than that of control group (P < 0.05). The disappearance time of fever, cough, sputum and lung moist rales in observation group was shorter than that in control group (P < 0.05). After treatment, the peak expiratory flow (PEF), maximum mid-expiratory flow (MMEF) and forced vital capacity (FVC) in the massage group were higher than those in the control group (P < 0.05). The levels of serum C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the massage group were lower than those in the control group after treatment (P < 0.05). After treatment, CD3+, CD4+, CD4+/CD8+ in the massage group were higher than those in the control group (P < 0.05), and CD8+ was lower than that in the control group (P < 0.05). There was nosignificant difference in the total incidence of adverse reactions between the massage group and the western medicine group (P>0.05).
    Conclusion Massage based on syndrome differentiation combined with western medicine can effectively relieve fever, cough and other symptoms of RMPP children, reduce inflammatory response, improve lung function and immune function, and has less adverse reactions.

     

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