腹腔镜下袖状胃切除术对肥胖型多囊卵巢综合征的疗效分析

胡扬喜; 刘岩; 李梦竹; 董星; 李冉; 王文娟; 叶建平; 刘寒松

doi:10.7619/jcmp.20234176

腹腔镜下袖状胃切除术对肥胖型多囊卵巢综合征的疗效分析

Efficacy analysis of laparoscopic sleeve gastrectomy in treating patients with obese polycystic ovary syndrome

摘要

摘要:
目的观察腹腔镜下袖状胃切除术（LSG）对合并肥胖的多囊卵巢综合征（PCOS）患者的治疗效果。
方法回顾性分析接受LSG手术合并肥胖的PCOS患者60例的临床资料，观察术后患者PCOS缓解情况。
结果 60例患者术前体质量指数（BMI）（39.4±5.4）kg/m²，年龄（26.3±6.1）岁，均成功完成LSG。术后随访12~18个月，50例（83.3 %）月经周期恢复正常，平均恢复时间为术后（4.5±2.2）个月，其中7例术后自然妊娠。35例术前超声提示卵巢多囊样变（PCOM），术后29例（82.9 %）恢复正常，平均恢复时间（6.3±2.8）个月。31例合并高雄激素血症，术后18个月29例（93.5 %）睾酮降至正常范围；术后18个月BMI（26.47±4.70）kg/m²，平均体质量下降（32.4±7.4）%。
结论 LSG是治疗肥胖型PCOS的一种安全有效的方法。

Abstract:
Objective To observe the therapeutic effect of laparoscopic sleeve gastrectomy (LSG) in treating patients with obesity and polycystic ovary syndrome (PCOS).
Methods In this retrospective analysis, clinical materials of 60 patients with obesity and PCOS by LSG were analyzed, and postoperative improvements of PCOS symptoms were observed.
Results A total of 60 patients had a preoperative mean body mass index (BMI) of (39.4±5.4) kg/m² and an average age of (26.3±6.1) years old, and all of them successfully completed LSG. After follow-up of 12 to 18 months, 50 cases (83.3%) had normalized menstrual cycles, with an average recovery time of (4.5 ±2.2) months after surgery, and 7 cases had natural pregnancy after surgery. Before surgery, ultrasound results in 35 patients indicated polycystic ovarian morphology (PCOM), and 29 cases (82.9%) regained normal ovarian status with an average recovery duration of (6.3±2.8) months. Complicated hyperandrogenemia was observed in 31 patients, and 29 cases (93.5%) exhibited normalization of testosterone levels within 18 months after surgery. At 18 months after surgery, the BMI was (26.47±4.70) kg/m², the average weight loss was (32.4±7.4) %.
Conclusion LSG is a safe and effective treatment for obese PCOS.

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