Objective  To investigate the effects of single-port laparoscopic extraperitoneal ligation on surgical indexes, intestinal mucosal barrier function and recurrence rate in children with pediatric inguinal hernia.

Methods  A total of 86 children with pediatric inguinal hernia in the hospital from February 2019 to June 2021 were randomly divided into control group (n=43) and study group (n=43). The study group performed single-port laparoscopic extraperitoneal ligation, while the control group received traditional open surgery. The ratio of urinary lactulose to mannitol (L/M) was measured by high-performance liquid chromatography; serum diamine oxidase (DAO) level was detected by enzyme-linked immunosorbent assay; serum D-lactic acid level was detected by enzymatic spectrophotometry; pain was assessed by the Visual Analogue Scale (VAS); surgical indicators, complications and postoperative recurrence rate were compared between the two groups.

Results  Compared with the control group, the study group had significant reduction in operation time, intraoperative blood loss, time to first flatus, and postoperative hospital stay (P < 0.05); in both groups, the VAS score, L/M, DAO level and serum D-lactic acid level decreased significantly after operation, and these indexes after operation in the study group were significantly lower than those in the control group (P < 0.05); the incidence of complications in the study group was 4.65%(2/43), which was significantly lower than 20.93%(9/43) in the control group (P=0.024).

Conclusion  Single-port laparoscopic extraperitoneal ligation is benefit for the treatment of children with pediatric inguinal hernia, which has advantages of fewer bleeding, less pain, fewer complications, faster recovery of intestinal mucosal barrier function, and lower recurrence rate.