非瓣膜性心房颤动的急性缺血性脑卒中患者的甲状腺激素水平分析

鲁远君; 栾梅; 付敏; 盘毓旻; 刘妍汐; 宋金玲; 曾建涛

doi:10.7619/jcmp.20233711

非瓣膜性心房颤动的急性缺血性脑卒中患者的甲状腺激素水平分析

Thyroid hormone levels in patients with acute ischemic stroke and non-valvular atrial fibrillation

摘要

摘要:
目的分析非瓣膜性心房颤动(NVAF) 的急性缺血性脑卒中(AIS)患者的甲状腺激素水平。
方法选取121例AIS患者，分为NVAF组(NVAF的AIS患者)和对照组(无房颤的AIS患者)。测定并比较2组患者的血清三碘甲状腺原氨酸(T₃)、游离三碘甲状腺原氨酸(FT₃)、甲状腺素(T₄)、游离甲状腺素(FT₄)和促甲状腺激素(TSH)水平。比较2组患者的生存情况。
结果 NVAF组血清T₃水平低于对照组，差异有统计学意义(P < 0.05)。2组血清FT₃、T₄、FT₄和TSH水平比较，差异无统计学意义(P>0.05)。2组患者的生存情况比较，差异无统计学意义(P>0.05)。
结论 NVAF与AIS患者的血清T₃水平有关。NVAF与AIS患者的死亡风险无相关性。

Abstract:
Objective To analyze the thyroid hormone levels in patients with acute ischemic stroke (AIS) and non-valvular atrial fibrillation (NVAF).
Methods A total of 121 patients with AIS were selected, and were divided into NVAF group (AIS patients with NVAF) and control group (AIS patients without atrial fibrillation). Serum levels of triiodothyronine (T₃), free triiodothyronine (FT₃), thyroxine (T₄), free thyroxine (FT₄) and thyroid stimulating hormone (TSH) in two groups were measured and compared. The survival of the two groups was compared.
Results The serum T₃ level in the NVAF group was significantly lower than that in the control group (P < 0.05). There were no significant differences in serum FT₃, T₄, FT₄ and TSH levels between the two groups (P>0.05). There was no significant difference in survival between the two groups (P>0.05).
Conclusion NVAF is associated with serum T₃ levels in AIS patients. There is no correlation between the risk of death and NVAF in AIS patients.

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