老年人肌少症患病情况调查及其与老年衰弱综合征的相关性分析

Investigation on prevalence of sarcopenia in elderly people and its correlation with geriatric frailty syndrome

  • 摘要:
    目的  调查成都市成华区某社区老年人肌少症患病情况并分析其与老年衰弱综合征的关系。
    方法  选取成都市成华区某社区586例老年人为研究对象, 对其进行老年综合评估,包括一般资料调查、人体测量(身高、体质量、握力、步速、骨骼肌等)和衰弱筛查量表调查。评估肌少症及老年衰弱综合征发生情况,分析肌少症与老年衰弱综合征的关系。
    结果  83例被诊断为肌少症,肌少症患病率为14.98%。肌少症组与正常组的性别、受教育程度、吸烟、饮酒及基础疾病情况比较,差异均无统计学意义(P>0.05)。与正常组相比,肌少症组年龄60~74岁者比率更低, 75~84岁及≥85岁者比率更高,老年衰弱综合征发生率更高,差异有统计学意义(P < 0.05)。与正常组比较,肌少症组的握力、步速、四肢骨骼肌量及四肢骨骼肌指数(ASMI)更低,差异有统计学意义(P < 0.05)。多因素分析显示,年龄、体质量指数(BMI)、老年衰弱综合征均是肌少症的影响因素(P < 0.05)。
    结论  成都市成华区某社区老年人肌少症的患病率较高,肌少症与老年衰弱综合征的发生密切相关。

     

    Abstract:
    Objective  To investigate the prevalence of sarcopenia in the elderly people in a community of Chenghua District of Chengdu city and analyze its relationship with geriatric frailty syndrome.
    Methods  A total of 586 elderly people in a community of Chenghua District of Chengdu city were selected as research objects for comprehensive geriatric assessment, including general data survey, anthropometric measurements (height, weight, grip strength, pace and skeletal muscle), and frailty screening scale survey. Incidence conditions of sarcopenia and geriatric frailty syndrome were evaluated, and the relationship between sarcopenia and geriatric frailty syndrome was analyzed.
    Results  Totally 83 cases were diagnosed as sarcopenia, and the prevalence of sarcopenia was 14.98%. There were no significant differences in gender, education level, smoking, alcohol consumption and basic diseases between the sarcopenia group and the normal group (P>0.05). Compared with the normal group, the sarcopenia group had a significant lower ratio of patients aged 60 to 74 years old, a significant higher ratio of patients aged 75 to 84 years old and ≥85 years old, and a significant higher incidence of geriatric frailty syndrome (P < 0.05). Compared with the normal group, the sarcopenia group had significant lower grip strength, pace, skeletal muscle mass of the four limbs, and appendicular skeletal muscle index (ASMI) (P < 0.05). Multivariate analysis showed that age, body mass index (BMI) and geriatric frailty syndrome were influencing factors for sarcopenia (P < 0.05).
    Conclusion  Prevalence of sarcopenia in the elderly people in a community of Chenghua District of Chengdu city is relatively high, and sarcopenia is closely correlated with the occurrence of geriatric frailty syndrome.

     

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