Abstract: Diarrhea is one of the most common complications during enteral nutrition treatment. It is of great significance to clarify the risk factors of diarrhea in enteral nutrition, build a risk prediction model, and implement early warning management of diarrhea risk in patients with enteral nutrition. This paper summarized the construction methods, evaluation indicators, advantages and limitations and other aspects by searching the literature on the risk prediction model of enteral nutrition-associated diarrhea at home and abroad, so as to promote the construction of the risk prediction model of enteral nutrition-associated diarrhea and promote the implementation of clinical risk early warning management measures.