咽喉反流中胃食管反流病相关诊断与治疗研究进展

Research progress on related diagnosis and treatment of gastroesophageal reflux disease in laryngopharyngeal reflux

  • 摘要: 咽喉反流(LPR)是指胃内容物反流到喉部和咽部,临床上表现为异物感、发音困难和吞咽困难等各种咽喉症状。传统的LPR诊断方法基于临床病史和喉镜检查,包括假声带沟、慢性咽喉炎、后联合肥大和黏膜分泌物增厚等表现。由于LPR在发病机制上与胃食管反流病(GERD)相关,且在接受GERD相关治疗后, LPR症状会得到一定缓解,部分学者将LPR归为GERD的食管外症状。尽管目前存在将两者区分开的主流观点,但一些GERD的诊疗方法也可用于LPR的诊断和治疗。本文综述近年来与LPR和GERD相关的诊断和治疗进展,并提出合理的诊疗流程,旨在为未来诊断和治疗LPR提供参考。

     

    Abstract: Laryngopharyngeal reflux (LPR) refers to the backflow of stomach contents into the throat and pharynx, clinically presenting with various throat symptoms such as a sensation of foreign body, difficulty in pronunciation and swallowing. Traditional methods for diagnosing LPR are based on clinical history and laryngoscopic examination, which include findings such as vocal cord groove, chronic pharyngolaryngitis, posterior laryngitis, and increased mucosal secretions. As LPR is closely related to gastroesophageal reflux disease (GERD) in terms of pathogenesis, and LPR symptoms can be relieved to some extent after receiving GERD-related treatment, some scholars also classify LPR as an extra-esophageal symptom of GERD. Although there is currently a mainstream view of distinguishing the two diseases, some diagnostic and therapeutic methods for GERD can also be used for the diagnosis and treatment of LPR. This paper aimed to review the recent advances in the diagnosis and treatment of LPR and GERD, and propose a rational diagnostic and therapeutic process as a reference for diagnosis and treatment of LPR in the future.

     

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