Objective To explore the effect of radiation exposure after iodine-125 implantation on the blood indicators of nursing staff in wards, and to provide basis for improving the radiation protection of nursing staff.

Methods Peripheral blood parameters of the nursing staff(experimental group) in the ward who were exposed to iodine-125 after implantation were monitored, and the blood parameters of the nursing staff(control group) in the ward without particle implantation during the same period were compared and analyzed. In addition, the results of gamma ray exposure from different angles and distances in patients after iodine-125 implantation were compared in conditions of lead shielding or lead-free shielding on the same day.

Results The results of the peripheral blood parameters in the experimental group were lower than those in the control group (P>0.05). Under the condition of lead-free shielding, the radiation dose measured at a distance of 100 cm from the puncture site was (10.6±2.6) uSv/h, which was close to the natural background radiation dose measured by γ-rays. Under the condition of lead shielding, the radiation dose measured at a distance of 15 cm was (10.4±2.0) uSv/h, which was close to the natural background radiation dose measured by γ-rays.

Conclusion After using lead shielding, post-implantation radiation exposure from iodine-125 has no significant impact on the peripheral blood parameters of the nursing staff in the ward and can effectively reduce the safe radiation distance.