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影像学工具诊断酒精引起的精神和行为障碍的价值分析

Value of imaging tools in the diagnosis of mental and behavioral disorders caused by alcohol

    摘要
  • 摘要:
    目的  分析动态脑电图(AEEG)联合磁共振成像(MRI)诊断酒精引起的精神和行为障碍的价值。
    方法  将2020年7月—2022年5月162例酒精所致精神和行为障碍患者设为观察组，另外根据观察组患者性别、年龄匹配同期来院体检的健康者55例为对照组。2组受试者均接受AEEG、MRI检查，比较2组受试者人口学资料，记录AEEG、MRI检查结果。采用二元Logistic回归分析探讨酒精所致精神和行为障碍患者的影响因素，绘制受试者工作特征(ROC)曲线，分析AEEG与MRI单独和联合诊断酒精所致的精神和行为障碍的价值。
    结果  观察组AEEG检查异常率为93.83%, 高于对照组的9.09%, 差异有统计学意义(P < 0.05)。观察组AEEG轻度异常率为80.86%, 中度异常率为9.88%, 重度异常率为3.09%。观察组头颅MRI检查结果异常者151例，正常者11例，对照组异常者2例，正常者53例，观察组异常率高于对照组，差异有统计学意义(P < 0.05)。Logistic回归分析结果显示, AEEG、MRI、独居、汉密尔顿抑郁量表(HAMD-17)评分、汉密尔顿焦虑量表(HAMA)评分是酒精所致的精神和行为障碍的影响因素(P < 0.05)。ROC曲线结果显示, AEEG、MRI单独和联合诊断酒精所致的精神和行为障碍的曲线下面积(AUC)分别为0.930、0.948、0.994。
    结论  酒精所致的精神和行为障碍患者存在明显AEEG、MRI异常, AEEG、MRI结果对诊断精神和行为障碍有一定临床参考价值，且两者联合诊断的精准度更高。

     

    Abstract:
    Objective  To analyze the value of amplitude dynamic electroencephalography (AEEG) combined with magnetic resonance imaging (MRI) in the diagnosis of alcohol induced mental and behavioral disorders.
    Methods  A total of 162 patients with mental and behavioral disorders caused by alcohol from July 2020 to May 2022 were randomly selected as observation group. A total of 55 healthy patients who came to the hospital for physical examinations at the same time matched with gender and age in the observation group were selected as control group. Both groups received AEEG and MRI examinations. The demographic data, AEEG and MRI examination results of the two groups were compared. The influencing factors of mental and behavioral disorders caused by alcohol were analyzed by binary Logistic regression. The receiver operating characteristic (ROC) curve was drawn to analyze the value of AEEG and MRI alone and their combination in diagnosing mental and behavioral disorders caused by alcohol.
    Results  The abnormal rate of AEEG in the observation group was 93.83%, which was significantly higher than 9.09% in the control group (P < 0.05). In the observation group, the mild abnormality rate of AEEG was 80.86%, the moderate abnormality rate of AEEG was 9.88%, and the severe abnormality rate of AEEG was 3.09%. There were 151 abnormal cases and 11 normal cases in the observation group, 2 abnormal cases and 53 normal cases in the control group. The abnormal rate in the observation group was significantly higher than that in the control group (P < 0.05). Logisticregression analysis showed that AEEG, MRI, living alone, Hamilton Depression Scale (HAMD-17) score, Hamilton Anxiety Scale (HAMA) score were the influencing factors of mental and behavioral disorders induced by alcohol (P < 0.05). ROC curve results showed that the area under the curve (AUC) of AEEG or MRI alone and their joint diagnosis for alcohol induced mental and behavioral disorders was 0.930, 0.948 and 0.994, respectively.
    Conclusion  The patients with mental and behavioral disorders caused by alcohol have obvious AEEG and MRI abnormalities. The results of AEEG and MRI have certain clinical reference value for the diagnosis of mental and behavioral disorders, and their combined diagnosis has higher accuracy.

     

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