连续菱形肌-肋间肌阻滞用于胸腔镜术后镇痛的效果评价

Effect evaluation of continuous rhomboid intercostal block in analgesia after thoracoscopic surgery

  • 摘要:
    目的 评价连续菱形肌-肋间肌阻滞(CRIB)用于胸腔镜术后镇痛的效果。
    方法 将120例胸腔镜手术患者随机分为CRIB组、单次菱形肌-肋间肌阻滞组(SRIB组)和患者自控静脉镇痛组(PCIA组), 每组40例。CRIB组患者在出室前实施CRIB; SRIB组患者在出室前实施SRIB; PCIA组患者在出室前连接PCIA镇痛泵。术后1、2、6、12、24 h时, 采用视觉模拟评分(VAS)评估患者静止状态和活动状态下的术后疼痛程度。术后24 h时, 采用40项恢复质量评分量表(QoR-40)评估患者术后恢复质量。记录术后24 h内补救镇痛例数、首次补救镇痛时间、麻醉复苏室(PACU)停留时间和术后住院时间。记录患者术后恶心呕吐(PONV)、头晕、皮肤瘙痒、气胸、呼吸困难等不良反应发生情况。
    结果 最终纳入118例患者, CRIB组、SRIB组各39例, PCIA组40例。SRIB组患者静止状态下、活动状态下的术后2 h的VAS评分低于CRIB组、PCIA组患者, 差异有统计学意义(P < 0.05)。CRIB组患者静止状态下、活动状态下的术后12、24 h的VAS评分低于SRIB组、PCIA组患者, 差异有统计学意义(P < 0.05)。CRIB组、SRIB组患者活动状态下各时点VAS评分低于PCIA组患者, 差异有统计学意义(P < 0.05)。SRIB组患者活动状态下的术后12、24 h的VAS评分低于PCIA组患者, 差异有统计学意义(P < 0.05)。CRIB组、SRIB组患者术后24 h QoR-40总分高于PCIA组患者, CRIB组患者术后24 h QoR-40总分高于SRIB组患者, 差异有统计学意义(P < 0.05)。CRIB组患者补救镇痛例数少于SRIB组和PCIA组患者, 差异有统计学意义(P < 0.05)。CRIB组患者首次补救镇痛时间长于SRIB组、PCIA组患者, 差异有统计学意义(P < 0.05)。PCIA组患者PONV、头晕、皮肤瘙痒发生率高于CRIB组、SRIB组患者, 差异有统计学意义(P < 0.05)。
    结论 CRIB是一种具有良好术后镇痛效果的镇痛方法, 能够改善胸腔镜术后恢复质量。

     

    Abstract:
    Objective To evaluate the effect of continuous rhomboid intercostal block (CRIB) in postoperative analgesia of patients with thoracoscopic surgery.
    Methods A total of 120 patients with thoracoscopic surgery were randomly divided into CRIB group, single rhomboid intercostal block group (SRIB group) and patient-controlled intravenous analgesia group (PCIA group), with 40 cases in each group. Patients in the CRIB group received CRIB before leaving the operating room, patients in the SRIB group received SRIB before leaving the operating room, and patients in the PCIA group were asked to connect PCIA analgesia pump before leaving the operating room. At 1 hour, 2, 6, 12 and 24 hours after surgery, the Visual Analogue Scale (VAS) was used to assess the postoperative pain level of patients in both static and active conditions. At 24 hours after surgery, the 40-item Quality of Recovery Scale (QoR-40) was used to assess the patient's postoperative recovery quality. The number of cases with rescue analgesia within 24 hours after surgery, the time of the first rescue analgesia, the stay time in post-anesthesia care unit (PACU) and the postoperative hospital stay were recorded. Incidence conditions of adverse reactions such as postoperative nausea and vomiting (PONV), dizziness, pruritus, pneumothorax and dyspnea were recorded.
    Results Finally, 118 patients were included, including 39 cases in the CRIB group, 39 cases in the SRIB group, and 40 cases in the PCIA group. The VAS scores of patients at 2 hours after surgery in the SRIB group under static and active conditions were significantly lower than those in the CRIB and the PCIA groups (P < 0.05). The VAS scores of patients at 12 and 24 hours after surgery in the CRIB group in both static and active conditions were significantly lower than those in the SRIB and the PCIA groups (P < 0.05). The VAS scores of patients in the CRIB and SRIB groups at each time point under active condition were significantly lower than those in the PCIA group (P < 0.05). The VAS scores of patients at 12 and 24 hours after surgery under active condition in the SRIB group were significantly lower than those in the PCIA group (P < 0.05). The total scores of QoR-40 in the CRIB and the SRIB groups at 24 hours after surgery were significantly higher than that in the PCIA group, while the total score of QoR-40 in the CRIB group at 24 hours after surgery was significantly higher than that in the SRIB group (P < 0.05). The number of cases with rescue analgesia in the CRIB group was significantly less than that in the SRIB and PCIA groups (P < 0.05). The time of the first rescue analgesia in the CRIB group was significantly longer than that in the SRIB and PCIA groups (P < 0.05). The incidence rates of PONV, dizziness and pruritus in the PCIA group were significantly higher than those in the CRIB and SRIB groups (P < 0.05).
    Conclusion CRIB is an analgesic method with good postoperative analgesic effect, which can improve the quality of recovery after thoracoscopic surgery.

     

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