基于超声内镜诊断的脂肪胰新型预测评分系统的应用价值

Application value of a new predictive scoring system for fatty pancreas based on endoscopic ultrasound diagnosis

  • 摘要:
    目的 探讨新型评分系统用于临床诊断脂肪胰(FP)的可行性。
    方法 选取2021年4月—2022年6月扬州大学附属医院消化内科消化内镜中心行超声内镜(EUS)诊断者55例为研究对象, 经超声内镜分为FP组与非FP组。比较2组一般资料和生化指标。以脂肪肝、高甘油三酯血症、腹型肥胖共3个指标改良评分系统,采用受试者工作特征(ROC)曲线评估改良后新评分系统预测FP的可行性。
    结果 共纳入55例研究对象,其中FP组20例,非FP组35例。FP组腹围、体质量指数(BMI)、高脂血症占比和脂肪肝患病率大于或高于非FP组,差异有统计学意义(P < 0.05)。FP组甘油三酯、谷丙转氨酶、谷草转氨酶高于非FP组,高密度脂蛋白低于非FP组,差异有统计学意义(P < 0.05)。FP组合并代谢综合征参数平均数量、合并代谢综合征参数数量≥3个者占比多于或高于非FP组,差异有统计学意义(P < 0.05)。改良后新型评分系统预测FP的效能显著改善曲线下面积(AUC)由0.651上升至0.731。
    结论 改良后的新型评分系统可作为临床工作中预测FP的简易工具。

     

    Abstract:
    Objective To explore the feasibility of a new scoring system for the clinical diagnosis of the fatty pancreas(FP).
    Methods From April 2021 to June 2022, 55 patients who underwent endoscopic ultrasound (EUS) diagnosis in the Gastroenterology Center of the Affiliated Hospital of Yangzhou University were selected as research objects. The patients were divided into FP group and non-FP group by endoscopic ultrasound. The general data and biochemical parameters of the two groups were compared. Fatty liver, hypertriglyceridemia and abdominal obesity were used to be improved scoring system. Receiver operating characteristic (ROC) curve was used to evaluate the feasibility of the new improved scoring system in predicting FP.
    Results A total of 55 subjects were included, including 20 in the FP group and 35 in the non-FP group. The abdominal circumference, body mass index (BMI), proportion of hyperlipidemia and prevalence of fatty liver in the FP group were significantly more or higher than those in the non-FP group(P < 0.05). Triglyceride, alanine aminotransferase, aspartate aminotransferase in the FP group were significantly higher than those in the non-FP group, and high-density lipoprotein was significantly lower than that in the non-FP group (P < 0.05). The average number of FP combined with metabolic syndrome parameters and the proportion of the number of metabolic syndrome parameters ≥ 3 in the FP group were significantly more or higher than those in the non-FP group (P < 0.05). After improvement, the efficiency of the new scoring system in predicting FP was significantly improved (AUC increased from 0.651 to 0.731).
    Conclusion The improved scoring system can be used as a simple tool to predict FP in clinical work.

     

/

返回文章
返回