Abstract: Ovarian hyperstimulation syndrome (OHSS) is a serious complication in the process of ovulation induction, which may endanger the lives of patients. This paper discusses the care needs of OHSS patients in four aspects of physiology, emotion and psychology, social support and information during outpatient and inpatient treatments, analyzes three nursing management methods based on medical care, family support and peer support, points out the problems and development direction of each method, and hopes to provide reference information and ideas for nursing practice and scientific researches.