Objective  To explore application value of cesarean section with preserved fetal membrane sac in premature delivery of twin-pregnant women.

Methods  The clinical data of 20 twin-pregnant women who performed cesarean section with preserved fetal membrane sac due to premature delivery in North Jiangsu People's Hospital from 2019 to 2021 were retrospectively analyzed. Another 30 twin-pregnant women who performed conventional lower uterine section for delivery in twin-pregnant women in the same period were selected as control group. The differences of operation time, amniotic fluid volume, intraoperative blood loss, neonatal Apgar score, neonatal birth weight, neonatal asphyxia and other aspects were analyzed. The differences of surgical indicators and pregnancy outcomes between cesarean section with preserved fetal membrane sac and conventional new lower uterine were compared.

Results  The average operation time of the observation group was (37.63±10.85) min, which was significantly shorter than (50.00±10.50) min in the control group(P < 0.05). The intraoperative blood loss in the observation group was (384.21±229.16) mL, which was more than (373.33±163.86) mL in the control group, but no significant difference was observed (P>0.05). The mean creatine kinase level in neonates with completely preserved fetal sac was (247.50±85.19) U/dL, which was lower than (311.35±138.03) U/dL in the control group and the difference was statistically significant (P < 0.05). There were no significant differences in intraoperative blood loss and neonatal asphyxia between cesarean section with preserved fetal membrane sac and conventional new lower uterine section (P>0.05).

Conclusion  Cesarean section with preserved fetal membrane sac can shorten operation time, improve the outcome of premature twin pregnancy, and may have a positive effect in reducing myocardial injury in premature infants.