四川省自贡市成人癫痫患者生活质量及影响因素分析

Quality of life and its influencing factors in adult epileptic patients in Zigong City of Sichuan Province

  • 摘要:
    目的 分析自贡市成人癫痫患者的生活质量及其影响因素。
    方法 随机选择自贡市癫痫上报系统中城乡成人癫痫患者200例。描述癫痫患者人口学特征及相关临床资料; 评估癫痫患者的生活质量, 以及分析癫痫患者生活质量的相关影响因素。
    结果 纳入的200例自贡癫痫患者男、女占比分别为56.5%和43.5%, 其中青中年癫痫患者占比为78.0%; 大部分是务农者或农民工,占62.5%, 无业人群占比22.5%; 65.0%的患者为初中毕业,初中及以下人群占比84.0%; 未婚及离异者占比34.0%; 发作类型以全面性癫痫为主,占比79.0%。经癫痫生活质量量表评估,自贡市成人癫痫患者生活质量评分均数为56.64分。多因素线性回归分析显示,活动性癫痫、癫痫共病焦虑、抑郁、认知障碍是癫痫患者生活质量的不良影响因素(P < 0.05)。
    结论 自贡市成人癫痫患者生活质量较为低下,临床治疗除控制癫痫发作外,还需评估其癫痫共病焦虑、抑郁及认知障碍情况,并给予干预。

     

    Abstract:
    Objective To analyze the quality of life and its influencing factors of adult epilepsy patients in Zigong City.
    Methods A total of 200 urban and rural adults with epilepsy in Zigong City Epilepsy Reporting System were randomly selected. The demographic characteristics and related clinical data of epilepsy patients were described. The quality of life of patients with epilepsy was evaluated, and the related influencing factors of the quality of life of patients with epilepsy were analyzed.
    Results Among the 200 patients with epilepsy in Zigong, the proportions of males and females were 56.5% and 43.5%, respectively, and the proportion of young and middle-aged patients with epilepsy was 78.0%. Most of them were farmers or migrant workers, accounting for 62.5%, and unemployed people accounted for 22.5%. 65.0% of the patients were junior high school graduates, and 84.0% of the patients were junior high school or below. Unmarried and divorced people accounted for 34.0%; the main seizure type was generalized epilepsy, accounting for 79.0%. The mean score of quality of life of adult patients with epilepsy in Zigong City was 56.64 by Epilepsy Quality of Life Scale. Multivariate linear regression analysis showed that active epilepsy, epileptic comorbidities anxiety, depression and cognitive impairment were the adverse influencing factors of quality of life in epilepsy patients (P < 0.05).
    Conclusion The quality of life of adult epileptic patients in Zigong City is relatively low. In addition to controlling epileptic seizures, the clinical treatment also needs to evaluate the anxiety, depression and cognitive impairment of epileptic comorbidity, and intervention should be given.

     

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