Abstract:
Objective To explore the effect of position adjustment combined with pressure irrigation on irrigation effect of laparoscopic ovarian endometriosis cyst removal.
Methods A total of 66 patients undergoing laparoscopic ovarian endometriosis cyst removal surgery under general anesthesia were selected as study objects, and were divided into control group(n=33) and observation group(n=33) by random number table method. The control group was given 1000 mL saline for washing at 30° degree in Trendelenburg position. The observation group was adjusted the surgical position when washing on the basis of the control group, and given pressed washing in whole process. The levels of carbohydrate antigen 125 (CA125) and vascular endothelial growth factor (VEGF) in peritoneal fluid were detected and compared between the two groups after pneumoperitoneum establishment (before intervention) and after irrigation (after intervention).
Results Before intervention, the levels of CA125 and VEGF in the peritoneal fluid in the two groups showed no statistically differences (P>0.05). After intervention, the levels of CA125 and VEGF in the peritoneal fluid were lower than intervention before, and were lower in the observation group than those in the control group(P < 0.05). The difference value before and after intervention in CA125 and VEGF levels in the observation group was greater than that of the control group (P < 0.05).
Conclusion Postural adjustment combined with pressurized irrigation during laparoscopic ovarian endometriosis cyst removal can reduce the levels of CA125 and VEGF in peritoneal fluid, reduce the residue of exfoliated intimal cells in the pelvic cavity, and decrease the probability of diffusion of inner membrane cells.
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