Objective To investigate the clinical value of pterygium excision combined with conjunctival flap transplantation in treatment of pterygium.

Methods A total of 60 patients (72 eyes) with pterygium were selected as research objects, 30 patients (36 eyes) treated with pterygium excision combined with conjunctival flap transplantation were included in observation group, and 30 patients (36 eyes) treated with pterygium excision combined with amniotic membrane transplantation were included in control group. The tear film function parameters, including basal tear secretion length (5 min), tear film rupture time and fluorescein staining score were evaluated before operation and at 3 and 6 months after operation. On 1st, 3rd, 5th and 14th postoperative day, the ocular comfort of patients in the two groups were evaluated respectively. After 1 year of follow-up, the efficacy and recurrence of the two groups were compared.

Results There were no significant differences in the preoperative basal tear secretion length, tear film break-up time and fluorescein staining score between the two groups(P > 0.05). The tear film break-up time of the observation group was longer than that of the control group at 3 and 6 months after the operation, and the fluorescein staining score was lower than that in the control group (P < 0.05). The total scores of eye comfort on the 1st, 3rd, 5th, and 14th day after operation in the observation group were significantly lower than that in the control group (P < 0.05). There were no significant differences in curative effect and recurrence rate between the two groups at one year after operation (P < 0.05).

Conclusion Pterygium excision combined with conjunctival flap transplantation is effective in treatment of pterygium, and no serious complications occur.