Objective To explore application value of CT-guided Hook-wire puncture localization in thoracoscopic resection of small pulmonary ground-glass nodules.

Methods A total of 136 patients with pulmonary nodules were selected as study objects, and underwent thoracoscopic resection Among them, 80 cases (observation group) were treated with CT-guided Hook-wire puncture localization before surgery, and other 56 cases (control group) received CT routine body surface localization. The localization accuracy, surgical resection time, length of hospital stay, puncture success rate, puncture time, puncture depth, total incidence of complications and drainage time were compared between the two groups.

Results The positioning accuracy of the observation group was higher than that of the control group (P=0.002 8). The operative resection time and postoperative drainage time in the observation group were significantly shorter than those in the control group (P < 0.001 or P < 0.05). The puncture success rate of the observation group was 93.4%, which was significantly higher than 72.2% of the control group (P < 0.001). The puncture depth in the observation group was significantly lower than that in the control group (P < 0.05). The total incidence of complications in the observation group was 12.5%, which was significantly lower than 19.6% in the control group (P < 0.001).

Conclusion Preoperative CT-guided Hook-wire puncture localization has a high safety in thoracoscopic resection of small pulmonary ground-glass nodules, which can improve positioning accuracy and puncture success rate, shorten surgical resection time and postoperative drainage time, and reduce the occurrence of complications. It has a good clinical application value.