Objective To observe the effect of "Fenxiao Zoxie Method" for hyperuricemia complicated with metabolic syndrome.

Methods A total of 200 patients with metabolic syndrome were selected, and were randomly divided into observation group (n=100) and control group (n=100). Patients in the control group were given routine exercise and diet intervention, routine treatment of hypertension, diabetes, hyperlipidemia drugs, and were orally taken Pioglitazone Hydrochloride Capsules at a dose of 30 mg, one time a day for 60 d. In the observation group, Qushi Jiangzhuo Recipe was added on the basis of the treatment scheme of the control group. The relatedindexes, clinical efficacy, blood uric acid level and quality of life of two groups were compared before and after treatment.

Results There were no significant differences in fasting blood glucose (FBG), 2 h postprandial blood glucose (2 hPBG), glycosylated hemoglobin (HbA1c), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), serum total cholesterol (TC), systolic blood pressure (DBP), diastolic blood pressure (SBP), body weight, waist circumference and body mass index(BMI) between the two groups (P>0.05). At 60 days after treatment, HDL-C in the observation group was higher than that in the control group, and other metabolic syndrome-related indexes were lower than those in the control group (P < 0.05). After 60 days of treatment, the metabolic syndrome related indexes of the two groups were improved compared with those before treatment, and the differences were statistically significant (P < 0.05). The total effective rate of the observation group was 98.00%, which was significantly higher than 91.00% of the control group(P < 0.05). After treatment, the UA levels of the two groups were lower than those before treatment, and the UA level of the observation group was lower than that of the control group (P < 0.05). The World Health Organization Quality of Life (WHOQOL-100) scores of the two groups after treatment were higher than that before treatment, and the score was higher in the observation group than that of the control group (P < 0.05).

Conclusion Qushi Jiangzhuo Recipe based on "Fenxiao Zoxie Method" has good clinical efficacy for patients with hyperuricemia complicated with metabolic syndrome. It improves effective rates and quality of life of patients, and can provide a new and reliable way for the treatment of hyperuricemia complicated with metabolic syndrome.