Objective To observe the effect of special ultrafiltration dehydration device for heart failure in the treatment of patients with severe heart failure complicated with diuretic resistance.

Methods A total of 30 patients with severe heart failure and diuretic resistance were selected as research objects. All the patients were treated with diuretics, cardiotonics, vasodilators and other conventional drugs according to relevant guidelines, and they were treated with special ultrafiltration for heart failure after diuretic resistance. Diuretics were not used during ultrafiltration, and 40 mg furosemide injection was given intravenously at the 24th hour after ultrafiltration. The changes of cardiac function classification of New York Heart Association, dyspnea score, ankle circumference, body mass, urine volume, respiratory rate, heart rate, cardiac output, left ventricle ejection fraction, N-terminal pro-B-type natriuretic peptide (NT-proBNP) and renal function electrolyte were observed before and after ultrafiltration.

Results After special ultrafiltration technology for heart failure, the total effective rate was 100.0% in the improvement of cardiac function classification of New York Heart Association, dyspnea score and lower limb edema. Body mass, respiratory rate, heart rate, creatinine (CR) and NT-proBNP of patients decreased significantly after treatment, cardiac output, ejection fraction and urine volume increased after treatment compared with treatment before (P < 0.05). There were no significant differences in blood potassium and blood sodium of patients before and after treatment (P>0.05). No death occurred during the whole treatment.

Conclusion For patients with severe heart failure and diuretic resistance, special ultrafiltration dehydration device for heart failure can rapidly improve cardiac function and diuretic resistance, and the treatment process is safe.