IKAP健康管理模式对胃黏膜轻度异型增生患者病理形态和临床经过的影响

Influence of IKAP health management mode on pathological morphology and clinical course of patients with mild dysplasia of gastric mucosa

  • 摘要:
    目的 研究IKAP健康管理模式对胃黏膜轻度异型增生(MDGM)患者自我健康管理水平、病理形态和临床经过的影响。
    方法 选取确诊为MDGM的患者100例,随机分为干预组和对照组,每组50例。对照组给予常规医疗管理和抗幽门螺杆菌(Hp)治疗,干预组同时给予IKAP健康管理、常规医疗管理和抗Hp治疗。分析干预前后MDGM患者胃镜病理检查结果、抗Hp治疗效果以及自我健康管理水平。
    结果 干预后,干预组体检信念、体检行为、MDGM健康知识、MDGM健康行为、MDGM健康信念评分和总分均高于干预前和对照组,差异有统计学意义(P<0.05)。IKAP干预后, MDGM患者胃镜病理检查显示胃黏膜细胞和腺体无破坏,未见异型,极少量炎症细胞浸润。MDGM患者在干预组中逆转占比为80.0%(40/50),高于对照组的14.0%(7/50),差异有统计学意义(χ2=43.717, P<0.001)。干预后,干预组Hp阳性例数少于对照组,差异有统计学意义(χ2=8.038, P=0.004)。
    结论 IKAP健康管理模式能有效提高MDGM患者的自我健康管理水平和Hp感染治愈率,并促进患者康复。

     

    Abstract:
    Objective To study the effects of IKAP health management model on self-health management level, pathological morphology and clinical course of patients with mild dysplasia of gastric mucosa (MDGM).
    Methods A total of 100 patients diagnosed with MDGM were randomly divided into intervention group and control group, with 50 cases in each group. The control group received routine medical management and Helicobacter pylori (Hp) treatment, while the intervention group also received IKAP health management, conventional medical management drugs and Hp treatment. The results of gastroscopic pathological examination, anti-HP treatment effect and self-health management level of MDGM patients before and after intervention were analyzed.
    Results After intervention, physical examination belief, physical examination behavior, MDGM health knowledge, MDGM health behavior, MDGM health belief score and total score in the intervention group were significantly higher than those before intervention and control group (P < 0.05). After IKAP intervention, the gastric mucosa cells and glands of MDGM patients were not damaged, no atypia was observed, and very few inflammatory cells were infiltrated. The reversal proportion of MDGM patients in the intervention group was 80.0%(40/50), which was significantly higher than 14.0%(7/50) in the control group (χ2=43.717, P < 0.001). After intervention, the number of Hp positive cases in the intervention group was significantly less than that in the control group (χ2=8.038, P=0.004).
    Conclusion IKAP health management model can effectively improve the self-health management level and Hp infection cure rate of MDGM patients, and promote their recovery.

     

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