Objective To explore the effects of ozone autohemo-therapy combined with evidence-based nursing in patients with acute cerebral infarction and its prognosis.

Methods A total of 115 patients withacute cerebral infarction were selected as research objects, and were divided into experimental group and control group by random number table method and patients'personal will. Eight cases were lost in follow-up, and 49 cases were included in the experimental group and 58 cases in the control group. The control group was given routine treatment and nursing; On the basis of the control group, the experimental group was given ozone autohemo-therapy and evidence-based nursing. Clinical efficacy, systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate before and after treatment were compared between two groups. National Institutes of Health Stroke Scale (NIHSS), Mini-Mental State Examination (MMSE), Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) were used to assess the neurological injury and psychological state of thepatients. Patients were followed up for 6 months to evaluate their prognosis and quality of life.

Results The total effective rate of the experimental group was 97.96%, which was significantly higher than 86.21% of the control group (P <0.05 0.05). NIHSS, SAS and SDS scores of the experimental group were significantly lower than those of the control group, MMSE and quality of life scores were significantly higher than those of the control group (P <0.05 0.05).

Conclusion Ozone autohemo-therapy combined with evidence-based nursing has a significant clinical effect in patients with acute cerebral infarction, which can relieve nerve injury, improve their psychological state and prognostic life quality.