Objective  To explore the effects of mindfulness-based stress reduction on fatigue symptoms and qualityof sleep in elderly patients with lymphoma.

  Methods  A total of 100 elderly patients with lymphoma were selected and randomly divided into control group and observation group, with 50 cases in each group. The control group was treated with conventional therapy, while the observation group was treated with mindfulness-based stress reduction. The intervention effect, fatigue symptoms and quality of sleep were observed in both groups.

  Results  The total effective rate in the observation group was 90.0%, which was significantly higher than 50.0% in the control group (P < 0.05). After intervention, the scores of Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) in the observation group were (35.54±2.65) and (34.56±3.46) points, respectively, which were significantly lower than (46.38±2.95) and (43.36±3.74) points in the control group (P < 0.05). After intervention, the scores of items of the Cancer-related Fatigue Scale (CFS) and the Pittsburgh Sleep Quality Index (PSQI) in the observation group were significantly lower than those in the control group, while the scores of items of the Philadelphia Geriatric Center Confidence Scale (PGC-CS) were significantly higher than those in the control group (P < 0.05).

  Conclusion  Mindfulness-based stress reduction can effectively improve the symptoms of depression, anxiety and fatigue in elderly patients with lymphoma, and enhance the quality of sleep and happiness of patients.