帕金森病共患失眠患者应用睡眠限制疗法的效果

Effect of sleep restriction therapy in patients with insomnia disorder comorbid to Parkinson's disease

  • 摘要:
      目的  观察帕金森病共患失眠患者应用睡眠限制疗法的效果。
      方法  将90例帕金森病伴失眠患者随机分成观察组和对照组,其中退出或失访者4例,最终完成研究者86例,每组43例。除睡眠健康教育外,观察组进行睡眠限制疗法。对照组只采用睡眠健康教育,每周通过电话或网络对患者进行随访。采用匹兹堡睡眠质量指数量表(PSQI)、Epworth嗜睡量表(ESS)、帕金森病评定量表(UPDRS-Ⅲ)、汉密尔顿焦虑评定量表(HAMA)、汉密尔顿抑郁评定量表(HAMD)、生活质量量表(SF-36)评分评估睡眠状况、运动症状、情绪状态及生活质量。
      结果  2组总有效率比较,差异有统计学意义(P < 0.05)。干预后,2组PSQI、ESS、HAMA、HAMD评分比较,差异有统计学意义(P < 0.05)。干预后,观察组SF-36评分为(73.86±6.57)分,高于对照组的(45.21±7.31)分,差异有统计学意义(P < 0.05)。
      结论  睡眠限制疗法具有操作性强、易于学习掌握和推广等优势,可以提高帕金森病共患失眠患者的睡眠质量、情绪状态和生活质量。

     

    Abstract:
      Objective  To observe the effects of sleep restriction therapy (SRT) in patients withinsomnia disorder comorbid to Parkinson's disease.
      Methods  A total of 90 patients with insomnia disorder comorbid to Parkinson's disease were recruited in the study, 4 cases withdrew or lost in follow-up, and 86 cases were finally completed the study. They were randomly divided into treatment group and control group, with 43 cases in each group. Besides the sleep health education, the sleep restriction therapy was given in the treatment group. The control group only received sleep health education and was followed up weekly by telephone or Internet. Pittsburgh sleep quality index (PSQI), Epworth Sleepiness Scale (ESS), Parkinson's disease rating scale Part 3 (UPDRS-Ⅲ), Hamilton Anxiety Rating Scale (HAMA), Hamilton Depression Rating Scale (HAMD) and 36-item Shot-form Health Status Survey (SF-36) were used to evaluate the sleep status, motor symptoms, emotional state and quality of life of the patients.
      Results  The total effective rate of two groups showed a significant difference(P < 0.05). After intervention, there were statistically significant differences in PSQI, ESS, HAMA and HAMD scores between the two groups (P < 0.05). After intervention, the patients in the observation group scored (73.86±6.57) in SF-36, which was higher than (45.21±7.31) of the control group (P < 0.05).
      Conclusion  Sleep restriction therapy has high operability, and is easy to learn, master and popularize. It can improve sleep quality, emotional state and life quality of patients with insomnia disorder comorbid to Parkinson's disease.

     

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